Emergence of nalidixic acid resistance in Shigella sonnei isolated from patients having acute diarrheal disease: report from eastern province of Saudi Arabia.
نویسندگان
چکیده
During the 5 years of the study period (October 1999-October 2003), 110 strains of Shigella were isolated from fecal samples of patients having acute diarrheal diseases. Shigella sonnei phase 1 was the most prevalent (88/110, 80.0%) serotype. Resistance to nalidixic acid was not encountered from 1999-2002. Nalidixic acid resistance was observed in 6/13 (46.1%) of the S. sonnei phase 1 strains isolated from April-August 2003. Minimum inhibitory concentration to nalidixic acid among these strains was 48-96 microg/ml. All the six nalidixic acid resistant strains of S. sonnei phase 1 had reduced susceptibility (MIC 0.25 microg/ml) to ciprofloxacin.
منابع مشابه
A Comparison between Culture and Multiplex PCR for Detection and Identification of Shigella Species in Patients with Shigellosis from Isfahan Province in 2014-2015
Introduction: Awareness of the species of Shigella has particular importance in the way of dealing with an outbreak, controlling it, and treating patients. The purpose of this study was to use the Multiplex PCR method and comparison with the culture method to detect Shigella species, as well as analysing the antibiotic resistance pattern in its different species. Methods: Simultaneously, the fe...
متن کاملEmergence of nalidixic acid-resistant Shigella sonnei in acute-diarrhea patients on Andaman and Nicobar Islands, India.
Shigella infection has been occurring in both epidemic and sporadic forms on Andaman and Nicobar Islands in India (92 to 94°E longitude, 6 to 14°N latitude; Bay of Bengal). Although acute gastrointestinal infection clinically resembling shigellosis has been reported on the islands frequently, bacteriological surveillance was only started in 1994. The surveillance data showed that shigellosis is...
متن کاملPrevalence of nontyphoidal Salmonella serogroups and their antimicrobial resistance patterns in a university teaching hospital in Eastern Province of Saudi Arabia
BACKGROUND Nontyphoidal Salmonella (NTS) species are important food-borne pathogens that cause gastroenteritis and bacteremia, and are responsible for a huge global burden of morbidity and mortality. The aim of this study was to investigate the prevalent serogroups and antibiotic resistance of NTS in our region. METHODS We reviewed the serogroup distribution and antimicrobial susceptibility p...
متن کاملChanging epidemiology of shigellosis and emergence of ciprofloxacin-resistant Shigellae in India.
Shigellosis is an important cause of morbidity and mortality in India. In contrast to what was reported for the developed world and Iran (1), where Shigella sonnei is common, the occurrence of nalidixic acid resistance is low, and no isolates have been determined to be resistant to fluoroquinolones, for the Indian subcontinent, Shigella flexneri continues to be the most common serogroup isolate...
متن کاملMagnitude of drug resistant shigellosis in Nepalese patients
BACKGROUND AND OBJECTIVES Shigella plays an important role as a causative organism of acute gastroenteritis, in children and others. Rapid emergence of antibiotic resistance warrants continuous monitoring of susceptibility pattern of bacterial isolates. We report here our findings about Shigella spp. isolates and their drug resistance patterns in Nepalese patients. MATERIALS AND METHODS The s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Japanese journal of infectious diseases
دوره 57 3 شماره
صفحات -
تاریخ انتشار 2004